DNA, Protein Synthesis & Cell Division
Key terms and steps tracing genetic information from DNA to trait, plus mitosis basics.
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Questions Covered in This Set
10 cards to master
What is the 'central dogma' of molecular biology?
DNA → RNA → protein → trait: DNA is transcribed into RNA, RNA is translated into protein, and proteins produce traits.
What are the DNA base-pairing rules?
A pairs with T (2 hydrogen bonds); C pairs with G (3 hydrogen bonds).
Name the three parts of a nucleotide.
A phosphate group, a deoxyribose sugar, and one nitrogen base (A, T, C, or G).
Why is DNA replication called 'semiconservative'?
Each new double helix keeps one original strand and one newly built strand. Helicase unzips the helix and DNA polymerase builds the new strands.
How does RNA differ from DNA (3 ways)?
RNA is single-stranded, uses ribose instead of deoxyribose, and uses uracil (U) instead of thymine (T).
What happens during transcription, and where?
In the nucleus, RNA polymerase reads a DNA template strand and builds a complementary mRNA strand (with U in place of T).
What is a codon and what reads it?
A codon is a group of three mRNA bases specifying one amino acid; the ribosome reads codons during translation while tRNA anticodons deliver matching amino acids.
What is the mRNA for the DNA template T A C G G C A A T?
A U G C C G U U A → Methionine (START), Proline, Leucine.
Compare a substitution mutation with a frameshift mutation.
A substitution swaps one base (e.g., sickle-cell's A→T). An insertion or deletion causes a frameshift, scrambling every codon downstream — usually severe.
What are the four stages of mitosis (PMAT)?
Prophase (chromosomes condense, envelope breaks down), Metaphase (chromosomes line up at the equator), Anaphase (sister chromatids pulled apart), Telophase (two nuclei re-form), followed by cytokinesis.